All-rounder Ben Stokes made 176 in England’s first-innings 469-9 declared and a dashing 78 not out on Monday that set up another declaration by home captain Joe Root.
Stokes then took two key wickets after Stuart Broad’s early treble helped reduce the West Indies to 37-4.
The third and deciding Test of a series that marks international cricket’s return from the coronavirus lockdown starts at Old Trafford on Friday.